The Myth of the Brain as a Video Camera

Before we discuss what current research tells us about memory and recall, it may be helpful to address a common misconception that emerged from the work ofCanadian neurosurgeon Wilder Penfield in the 1930s and 1940s. Penfield reported that during surgery, an electrical stimulation of the temporal lobe produced episodes of recall, almost like seeing movie clips. Many concluded that the brain ―videotaped‖ life, and to remember things, our memories simply needed to be prompted. But these epi...

 Genes Associated with Brain Volume

Identifying genetic variants influencing human brain structures may reveal new biological mechanisms underlying cognition and neuropsychiatric illness. The volume of the hippocampus is a biomarker of incipient Alzheimer's disease1, 2and is reduced in schizophrenia3, major depression4 and mesial temporal lobe epilepsy5. Whereas many brain imaging phenotypes are highly heritable6, 7, identifying and replicating genetic influences has been difficult, as small effects and the high costs of mag...